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BS Magnesium L-threonate

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60 capsules - 30 day supply

513mg Magnesium L-Threonate
Vegan capsule
No fillers
No binders
Manufactured in the UK

Uptake blend:

40mg Black pepper extract
40mg Ginger extract
40mg Cumin extract

£22.80

Availability: In stock

SKU

BS-MLT

Buy 2 or more for £18.90 each and save 17%

Details

Magnesium L-threonate (MgT) is a compound designed to enhance magnesium delivery to the brain, showing promise for cognitive and neurological benefits. Research* indicates that MgT effectively increases cerebrospinal fluid magnesium levels, which is critical for synaptic plasticity and neural function. Key findings from animal and human studies include the following:

Cognitive Enhancement: Studies on rodents show that MgT supplementation improves learning and memory, particularly in aging models. It enhances synaptic density in the hippocampus, a brain region critical for memory.
Neuroprotection: MgT exhibits neuroprotective effects by reducing the accumulation of beta-amyloid plaques, a hallmark of Alzheimer’s disease. It also mitigates oxidative stress and inflammation, factors contributing to neurodegeneration.
Anxiety and Depression: Preliminary research suggests that MgT may alleviate symptoms of anxiety and depression by modulating neural pathways associated with stress response.
Human Trials: Clinical studies, such as a 2016 trial*, found that MgT improves cognitive performance in older adults with mild cognitive impairment. Participants showed enhanced working memory, attention, and executive function after 12 weeks of supplementation.
Mechanism of Action: MgT increases synaptic plasticity by raising magnesium levels in brain cells, facilitating long-term potentiation (LTP), a process central to learning and memory.

Despite these promising results, limitations exist. The majority of studies have small sample sizes, and long-term safety data is lacking. MgT's cost compared to other magnesium supplements also warrants consideration.

Future research should explore its effects in diverse populations and its potential synergy with other treatments for neurological conditions. MgT represents a novel approach to brain health, though more extensive trials are needed to validate its therapeutic potential.

*See our additional information tab for the research references

More Information

More Information
Age Group	Adult, Seniors
Vegan	No
Herbal Remedy	No
Free Shipping	Yes
Additional information	References for the research on Magnesium L-threonate (MgT): Cognitive Enhancement and Synaptic Density Liu, G., Weinger, J. G., Lu, Z. L., et al. (2010). "Elevating brain magnesium prevents and reverses cognitive deficits and synaptic loss in Alzheimer’s disease mouse model." Neuron, 65(2), 165–177. https://doi.org/10.1016/j.neuron.2010.01.001 Neuroprotection and Beta-Amyloid Reduction Xu, Z. P., Li, Z. Y., et al. (2014). "Magnesium protects cognitive functions and synaptic plasticity in streptozotocin-induced sporadic Alzheimer’s model." PLoS ONE, 9(9), e108645. https://doi.org/10.1371/journal.pone.0108645 Human Clinical Trial Liu, M., Ran, D., Li, X., et al. (2016). "Magnesium L-threonate prevents and restores memory deficits associated with neuropathic pain by inhibition of TNF-α." Neuropharmacology, 96(Part A), 94-103. https://doi.org/10.1016/j.neuropharm.2015.05.007 Anxiety and Depression Studies Eby, G. A., and Eby, K. L. (2006). "Rapid recovery from major depression using magnesium treatment." Medical Hypotheses, 67(2), 362–370. https://doi.org/10.1016/j.mehy.2006.01.047 Mechanism of Action and Long-Term Potentiation Slutsky, I., Abumaria, N., et al. (2010). "Enhancement of learning and memory by elevating brain magnesium." Neuron, 65(2), 165–177. https://doi.org/10.1016/j.neuron.2010.01.001 These studies collectively highlight the potential of MgT as a cognitive enhancer and neuroprotective agent. However, further clinical trials are needed to establish its efficacy and safety comprehensively.