{"product_id":"pure-tmg","title":"Manapura Pure TMG (Trimethylglycine) Supplement | Methylation \u0026 Cellular Health Support","description":"\u003ch2\u003eSupport Your Body's Most Essential Biochemical Process\u003c\/h2\u003e\u003cp\u003eMethylation is one of the most fundamental processes in human biology — occurring billions of times per second in every cell of your body. It governs gene expression, DNA repair, neurotransmitter production, detoxification, and cellular maintenance. When methylation is impaired, the downstream effects can touch virtually every system in the body.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTMG (Trimethylglycine)\u003c\/strong\u003e, also known as betaine, is one of the body's primary methyl donors — directly fuelling the methylation cycle and helping to maintain optimal physiological function. It's particularly valued in longevity protocols as a complement to NMN and other NAD+ precursors, which can deplete methyl groups over time.\u003c\/p\u003e\u003cp\u003eManapura Pure TMG is third-party tested for purity on every batch, so you can be confident in exactly what you're taking.\u003c\/p\u003e\u003ch3\u003eKey Benefits\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMethylation support\u003c\/strong\u003e — acts as a primary methyl donor to fuel the body's methylation pathways\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDNA stability\u003c\/strong\u003e — supports DNA methylation, a key mechanism in gene regulation and repair\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHomocysteine regulation\u003c\/strong\u003e — helps convert homocysteine to methionine, supporting cardiovascular health\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLiver health\u003c\/strong\u003e — supports hepatic fat metabolism and liver function\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAthletic performance\u003c\/strong\u003e — research suggests TMG may support power output and exercise capacity\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNMN \u0026amp; NAD+ synergy\u003c\/strong\u003e — replenishes methyl groups consumed during NAD+ synthesis, making it an ideal companion supplement\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-party tested\u003c\/strong\u003e — every batch verified for purity and potency\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eWhy TMG Matters for Longevity\u003c\/h3\u003e\u003cp\u003eAs NMN supplementation increases NAD+ levels, it also consumes methyl groups in the process. Without adequate methyl donors like TMG, this can create an imbalance. Supplementing TMG alongside NMN is widely recommended in longevity circles to maintain healthy methylation balance and maximise the benefits of both compounds.\u003c\/p\u003e\u003ch3\u003eHow to Use\u003c\/h3\u003e\u003cp\u003eTake as directed on the product label, with food. For best results, use consistently — particularly if you are also supplementing with NMN or other NAD+ precursors.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eManapura — premium longevity supplements, crafted with purpose.\u003c\/em\u003e\u003c\/p\u003e","brand":"Manapura","offers":[{"title":"Default Title","offer_id":54208741048662,"sku":"MP-TMG-C-060-B","price":25.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0920\/3213\/9606\/files\/manapura-longevity-03-pure-tmg-500mg-box.png?v=1781601079","url":"https:\/\/total-wellness.co.uk\/products\/pure-tmg","provider":"Total Wellness","version":"1.0","type":"link"}